Late effects

Feasibility of serial neurocognitive assessment using Cogstate during and after therapy for childhood leukemia

Authors: Peter D Cole, Soo Young Kim, Yuelin Li, Adrian Schembri, Kara M Kelly, Maria-Luisa Sulis, Lynda Vrooman, Jennifer J G Welch, Sameera Ramjan, Lewis B Silverman, Stephen A Sands

Journal: Supportive Care in Cancer

Year Published: 2023

Purpose Neurocognitive impairment is frequently observed among survivors of childhood acute lymphoblastic leukemia (ALL) within the domains of attention, working memory, processing speed, executive functioning, and learning and memory. However, few studies have characterized the trajectory […]

An Integrated Analysis of Clinical, Genomic, and Imaging Features Reveals Predictors of Neurocognitive Outcomes in a Longitudinal Cohort of Pediatric Cancer Survivors, Enriched with CNS Tumors (Rad ART Pro)

Authors: Cassie Kline, Schuyler Stoller, Lennox Byer, David Samuel, Janine M Lupo, Melanie A Morrison, Andreas M Rauschecker, Pierre Nedelec, Walter Faig, Dena B Dubal, Heather J Fullerton, Sabine Mueller

Journal: Frontiers in Oncology

Year Published: 2022

Background: Neurocognitive deficits in pediatric cancer survivors occur frequently; however, individual outcomes are unpredictable. We investigate clinical, genetic, and imaging predictors of neurocognition in pediatric cancer survivors, with a focus on survivors of central nervous system […]

Monitoring neurocognitive functioning in childhood cancer survivors: evaluation of CogState computerized assessment and the Behavior Rating Inventory of Executive Function (BRIEF)

Authors: Lyn M. Balsamo, Hannah-Rose Mitchell, Wilhelmenia Ross, Catherine Metayer, Kristina K. Hardy & Nina S. Kadan-Lottick

Journal: BMC Psychology

Year Published: 2019

Background: Many childhood cancer survivors develop neurocognitive impairment, negatively affecting education and psychosocial functioning. Recommended comprehensive neuropsychological testing can be time- and cost- intensive for both institutions and patients and their families. It is important to […]

Feasibility of baseline neurocognitive assessment using Cogstate during the first month of therapy for childhood leukemia

Authors: Stephen A Sands, Brian T Harel, Mirko Savone, Kara Kelly, Veena Vijayanathan, Jennifer Greene Welch, Lynda Vrooman, Lewis B Silverman, Peter D Cole

Journal: Supportive Care in Cancer

Year Published: 2016

Purpose: Neurocognitive impairment is frequently observed among acute lymphoblastic leukemia (ALL) survivors within the domains of intelligence, attention, processing speed, working memory, learning, and memory. However, few have investigated treatment-induced changes in neurocognitive function during the […]

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