Acute lymphoblastic leukemia

Feasibility of Utilizing a Brief Neurocognitive Battery in 3-Year-Old Patients During Treatment for Acute Lymphoblastic Leukemia

Authors: Sameera Ramjan, Peter D Cole, Melanie Blair-Thies, Lewis B Silverman, Amy Fredrickson, Adrian Schembri, Jennifer J Greene Welch, Justine Kahn, Kara M Kelly, Thai-Hoa Tran, Bruno Michon, Lisa Gennarini, Stephen A Sands

Journal: Pediatric Blood & Cancer

Year Published: 2024

Treatment of acute lymphoblastic leukemia (ALL) is associated with neurocognitive deficits in young children. While computerized measures have been utilized in pediatric oncology research, they exclude patients below the age of 4 years. Patients enrolled on […]

Impaired neurocognitive functioning 3 months following diagnosis of high-risk acute lymphoblastic leukemia: A report from the Children’s Oncology Group

Authors: Kristina K Hardy, John A Kairalla, Anthony R Gioia, Hannah S Weisman, Meera Gurung, Robert B Noll, Pamela S Hinds, Emily Hibbitts, Wanda L Salzer, Michael J Burke, Naomi J Winick, Leanne Embry

Journal: Pediatric Blood & Cancer

Year Published: 2023

Purpose Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer diagnosis. Cognitive late effects develop in 20%-40% of ALL survivors, but the course of declines is unclear. The aim of this paper is to characterize […]

Feasibility of serial neurocognitive assessment using Cogstate during and after therapy for childhood leukemia

Authors: Peter D Cole, Soo Young Kim, Yuelin Li, Adrian Schembri, Kara M Kelly, Maria-Luisa Sulis, Lynda Vrooman, Jennifer J G Welch, Sameera Ramjan, Lewis B Silverman, Stephen A Sands

Journal: Supportive Care in Cancer

Year Published: 2023

Purpose Neurocognitive impairment is frequently observed among survivors of childhood acute lymphoblastic leukemia (ALL) within the domains of attention, working memory, processing speed, executive functioning, and learning and memory. However, few studies have characterized the trajectory […]

Feasibility of baseline neurocognitive assessment using Cogstate during the first month of therapy for childhood leukemia

Authors: Stephen A Sands, Brian T Harel, Mirko Savone, Kara Kelly, Veena Vijayanathan, Jennifer Greene Welch, Lynda Vrooman, Lewis B Silverman, Peter D Cole

Journal: Supportive Care in Cancer

Year Published: 2016

Purpose: Neurocognitive impairment is frequently observed among acute lymphoblastic leukemia (ALL) survivors within the domains of intelligence, attention, processing speed, working memory, learning, and memory. However, few have investigated treatment-induced changes in neurocognitive function during the […]

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